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Characterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing.

Identifieur interne : 001691 ( Main/Exploration ); précédent : 001690; suivant : 001692

Characterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing.

Auteurs : Christopher Cowled [Australie] ; Cameron R. Stewart ; Vladimir A. Likic ; Marc R. Friedl Nder ; Mary Tachedjian ; Kristie A. Jenkins ; Mark L. Tizard ; Pauline Cottee ; Glenn A. Marsh ; Peng Zhou ; Michelle L. Baker ; Andrew G. Bean ; Lin-Fa Wang

Source :

RBID : pubmed:25128405

Descripteurs français

English descriptors

Abstract

Bats are a major source of new and emerging viral diseases. Despite the fact that bats carry and shed highly pathogenic viruses including Ebola, Nipah and SARS, they rarely display clinical symptoms of infection. Host factors influencing viral replication are poorly understood in bats and are likely to include both pre- and post-transcriptional regulatory mechanisms. MicroRNAs are a major mechanism of post-transcriptional gene regulation, however very little is known about them in bats.

DOI: 10.1186/1471-2164-15-682
PubMed: 25128405


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<term>Gene Ontology</term>
<term>High-Throughput Nucleotide Sequencing</term>
<term>Introns</term>
<term>Inverted Repeat Sequences</term>
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<term>Séquences répétées inversées</term>
<term>Séquençage nucléotidique à haut débit</term>
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<term>Base Sequence</term>
<term>Binding Sites</term>
<term>Gene Ontology</term>
<term>High-Throughput Nucleotide Sequencing</term>
<term>Introns</term>
<term>Inverted Repeat Sequences</term>
<term>Male</term>
<term>Molecular Sequence Annotation</term>
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<term>Multigene Family</term>
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<term>Famille multigénique</term>
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<term>Sites de fixation</term>
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<div type="abstract" xml:lang="en">Bats are a major source of new and emerging viral diseases. Despite the fact that bats carry and shed highly pathogenic viruses including Ebola, Nipah and SARS, they rarely display clinical symptoms of infection. Host factors influencing viral replication are poorly understood in bats and are likely to include both pre- and post-transcriptional regulatory mechanisms. MicroRNAs are a major mechanism of post-transcriptional gene regulation, however very little is known about them in bats.</div>
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